From New England Journal of Medicine. 

Mark R. Elkins, M.H.Sc., Michael Robinson, Ph.D., Barbara R. Rose, Ph.D., Colin Harbour, Ph.D., Carmel P. Moriarty, R.N., Guy B. Marks, Ph.D., Elena G. Belousova, M.Appl.Sc., Wei Xuan, Ph.D., and Peter T.P. Bye, Ph.D. for the National Hypertonic Saline in Cystic Fibrosis (NHSCF) Study Group 

N Engl J Med 2006; 354:229-240January 19, 2006DOI: 10.1056/NEJMoa043900

A Controlled Trial of Long-Term Inhaled Hypertonic Saline in Patients with Cystic Fibrosis